Plain-English supplement analysis graded against the published research, including, often, the finding that the evidence doesn't support the product. No miracle claims. No pay-for-verdict. We tell you when to save your money.
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Every evidence claim links to its study on PubMed. Each ingredient is graded from strongest to limited, and the grade is set before any affiliate link is added. How we review
The sleep trial used 250 mg of elemental magnesium a day as bisglycinate, and the supplement limit is 350 mg. Here is how to read the label, when to take it, the side effects, and the medicines it interacts with.
Protoflow is sold for prostate support and prints every dose. Most of the formula is libido herbs, and its saw palmetto is about a quarter of the dose that failed to beat placebo in trials.
Flexi Move is sold for joint support, but its label is a 500 mg blend of tribulus, fenugreek, saw palmetto and other herbs normally found in testosterone products, with no doses shown. We do not recommend it for joint pain.
In large trials, semaglutide and tirzepatide helped people lose about 15% to 21% of their body weight over 68 to 72 weeks. The best-studied weight-loss supplements manage about 0 to 2 kg. The drugs have real side effects and the weight returns if you stop. Compounded copies are not FDA-approved.
GutSave is a daily capsule of fish collagen, cinnamon, sea moss, papaya seed, black cumin, colostrum and probiotics. The label shows every dose, and each is a fraction of what the trials used. Fibre has much better evidence for constipation.
Java Burn is now coffee drops with green tea, green coffee, L-carnitine and L-theanine in an undisclosed 550 mg blend. Those ingredients have shown about 1 to 2 kg of extra weight loss in trials, at doses the blend is unlikely to reach.
Measured is a US telehealth clinic that prescribes Wegovy, the Wegovy pill and Zepbound after an online assessment, and sells cheaper compounded versions. The branded drugs have strong trials. The real monthly cost is membership plus medicine, it serves 26 states, and there are no refunds.
ProvaDent is a chewable tablet with xylitol, cranberry and four unnamed probiotic strains. Oral probiotics have some support for gum bleeding, but the sales page shows no label, doses or strain names, so its claims cannot be checked.
FemiCore is a daily capsule of cranberry, bearberry, berberine, Mimosa pudica and five probiotics, all in two undisclosed blends. We found no trial showing any of them reduces bladder leaks. Pelvic floor training has much better evidence and costs little.
Joint Genesis is a one-a-day capsule of Mobilee hyaluronic acid, pine bark, boswellia, ginger and black pepper, with every dose on the label. The ingredients have small, mostly positive trials. The product itself has none, and exercise and diclofenac gel have better evidence for less money.
A melatonin sleep formula with every dose on the label. The 3 mg of melatonin has modest evidence; the 5-HTP rules out anyone on antidepressants, and the amino acids sit below their trial doses.
Berberine has the best trial record of any glucose supplement. This capsule uses 250 mg of dihydroberberine, a form with absorption data and no glucose trials, and berberine interacts with many common drugs.
Arctic Blast is a menthol and camphor rub. The DMSO the sales pages lead with is listed on the label as an inactive ingredient, and the trials behind each ingredient are thin. It may ease minor aches for a while. Diclofenac gel has far better evidence.
Melatonin has the strongest evidence and the most misunderstood dose. Magnesium helps a little, and the form matters less than the marketing says. Most of the rest is plausible but thin. An evidence-ranked guide, plus the free changes that beat every supplement here.
Beta-sitosterol is the single best-evidenced supplement ingredient for male urinary symptoms. A Cochrane review and a landmark Lancet trial back it. Here's what the studies actually measured, dose, and limits.
For most people, no. The largest independent trials and a pooled analysis of 3,803 patients found glucosamine barely beat placebo for knee pain. One branded form has better results, mostly from trials its maker funded. Here is what the evidence shows and what works better.
Finasteride and minoxidil are the two hair-loss drugs with years of placebo-controlled trials behind them. Both work for many men with pattern hair loss, finasteride slightly better over a year, and they can be combined. Finasteride carries sexual and mood side-effect warnings you should read first. Supplements like biotin and saw palmetto are far weaker.
A genuine 500 mg magnesium dose spread across seven forms. The trouble is that the sleep evidence for magnesium is thin, the split between forms is hidden, and one of the seven is magnesium oxide.
Magnesium is the most recommended mineral for sleep and one of the least well evidenced. The best meta-analysis pooled three trials in 151 people and rated the evidence low to very low. Here is what holds up, which form to pick, and who is most likely to notice anything.
Keeps is a US telehealth service that sells generic finasteride and minoxidil after an online consult. Those are the two hair-loss drugs with strong trial evidence, and its prices are reasonable. The drugs are the point; the service adds convenience. Read the finasteride side-effect evidence first, and note it does not serve the UK.
A melatonin-free sleep drink with every dose on the label. L-theanine and glycine are dosed like the trials; the rest are small doses or ingredients with no sleep evidence.
Two of its eight ingredients have real glucose trials behind them. The other six target energy and weight. The best-evidenced blood-sugar ingredient is missing entirely, and there is an interaction risk with diabetes medication that most reviews never mention.
The ingredients are mostly well tolerated on their own. The risk is what happens when two of them are added on top of diabetes medication, and the caffeine nobody expects to find in a blood-sugar product.
The ingredient list is unusually sensible for this category. The doses are the problem: melatonin sits below the studied range and everything else hides inside a 637 mg blend. Reasonable for mild trouble falling asleep, wrong for anyone on antidepressants.
The ingredients are mostly well tolerated, but one of them interacts with antidepressants and most reviews never mention it. What to expect, and the four groups who should not take this.
Gummies are the fastest-growing way to take melatonin and the format where the dose is hardest to trust. Pediatric melatonin ingestions rose 530% in a decade, and melatonin gummies carried 8.4 times the odds of a child developing symptoms compared with other gummy supplements.
Berberine has the strongest trial evidence, and it is the one most blended products leave out. An evidence-ranked guide to what actually moves glucose numbers, what no supplement can do, and the interactions that matter if you take medication.
More is not better, and most people take it at the wrong time. A meta-analysis of 26 trials mapped dose against effect: the benefit peaked around 4 mg, taken about three hours before bed rather than at bedtime.
An evidence-ranked guide to oral-health supplements: which strains and nutrients have real trial data for bleeding gums, plaque, and bad breath, what to do before buying anything, and the claims that should make you close the tab.
Receded gum tissue does not grow back on its own, and no supplement, oil, or rinse regrows it. What the research does support: stopping further recession, and surgical root coverage that genuinely works when it's warranted.
Some oral probiotic strains have genuine controlled-trial evidence for gum bleeding and bad breath. Others are riding on general-probiotic reputation with no human data at all. Here is which is which, and what the results actually mean.
An oral probiotic whose honest case rests on three of its five strains. The finished product is untested, the per-strain doses are hidden, and it won't regrow gums. A low-risk try for mild symptoms, and a waste of money for anyone expecting a cure.
An ingredient-by-ingredient look at ProstaVive against the published research, which parts of the formula have real trial evidence for urinary symptoms, which don't, and who should skip it entirely.
Powder vs drops is the surface difference. The real one: ProstaVive's urinary ingredients have controlled-trial evidence; Prostadine's marine botanicals mostly don't. Side-by-side comparison with citations.
Waking 2–3 times a night to urinate? An evidence-ranked guide for men: the free habit changes that work first, the two nutrients with real trial data, and when to see a doctor instead.
Evidence-first guides and reviews on bladder leaks, urgency and incontinence in women: what the trials show for pills sold online, why pelvic floor training comes first, and when to see a doctor.
Evidence-first reviews of blood-sugar supplements. What the trials actually show, what no supplement can do, and when to see a doctor instead.
Evidence-first reviews of oral-health supplements: probiotics for gums, plaque, and bad breath. Every strain graded against the published research.
Evidence-first guides and reviews on constipation, bloating and digestive supplements: what the label really contains, what the trials show at those doses, and which cheap options have better evidence.
Evidence-first guides and reviews for male and female pattern hair loss: the prescription drugs with real trials, the supplements without them, and when to see a doctor first.
Evidence-first reviews of joint pain products, pills and rubs alike. What the trials show, what they don't, and when a joint needs a doctor.
Evidence-first reviews of men's health supplements: prostate support and urinary symptoms, with every ingredient graded against published trials.
Evidence-first reviews of sleep supplements: melatonin, magnesium, and the calming botanicals, each graded against the published trials.
Evidence-first guides and reviews for weight loss: what the semaglutide and tirzepatide trials show, how weak most weight-loss supplements are, and when to see a doctor first.